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CIL56
  • 商城价格 登录后可查看价格
  • 货号 T4309
  • 品牌 TargetMol ( 生产厂家 )
  • CAS号 300802-28-2
  • 规格/包装 1 mL
  • 单位 瓶
  • 储存条件 -20度
  • 现货状态 现货
  • 数量

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CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyunsaturated fatty acids in HT-1080 cells in vitro.HT-1080 cells lacking acetyl-CoA carboxylase 1 (ACC1), the rate-limiting enzyme in fatty acid synthesis, exhibit 5-fold resistance to CIL56 treatment, indicating ACC1 activity sensitizes cells to CIL56-induced cell death.
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