Description
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex Product Details
Product Details
Isotype ControlAPC Rat IgG2b, κ Isotype CtrlReactivityMouseAntibody TypeMonoclonalHost SpeciesRatImmunogenγδTCR-positive T-T hybridoma D1FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.PreparationThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.Concentration0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.