官网：https://www.elabscience.cn/ ; 别称 ANXA5;Annexin V;Unconjugated Annexin V;Annexin-5;Anchorin CII;Calphobindin I;Endonexin II;Lipocortin V;Placental anticoagulant protein 4;Thromboplastin inhibitor;Vascular anticoagulant-alpha 表达系统 E.coli 序列 Met 1-Asp 320 蛋白编码 P81287 种属 Bovine 计算分子量 35.1 kDa 表观分子量 35 kDa 标签 N-His 纯度 > 95 % as determined by reducing SDS-PAGE. 内毒素 Please contact us for more information. 保存条件 Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. 运输条件 This product is provided as lyophilized powder which is shipped with ice packs. 制剂 Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. 复溶方法 Please refer to the printed manual for detailed information. 背景 Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli, and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.