Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and interleukin-4 signaling pathway. Phosphorylates STAT6, IRS1, IRS2 and PI3K.
Research Field
Signal Transduction
Product Categories
Primary antibody
Host
Rabbit
Reactivity
Human
Application
WB,ICC/IF
Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
Molecular Weight
Calculated MW: 125 kDa; Observed MW: 125 kDa
Clonality
Monoclonal Antibody
Clonality No.
R03-9I7
Isotype
IgG
Immunogen
A synthesized peptide derived from human JAK3
Purification
Affinity Chromatography
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.