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2,4,6-Trihydroxybenzaldehyde is a natural product. 2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice. It is also a potent antidiabetic agent. 2,4,6-Trihydroxybenzaldehyde has potential anticancer activity.