function:Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.,function:May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.,mass spectrometry: PubMed:9677337,polymorphism:There are 3 common alleles; ITIH1*1 with Glu-585/Gln-595, ITIH1*2 with Val-585/Arg-595 and ITIH1*3 with Glu-585/Arg-595.,PTM:Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.,PTM:The S-linked glycan is composed of two units of either Glc or Gal.,similarity:Belongs to the ITIH family.,similarity:Contains 1 VWFA domain.,subunit:I-alpha-I plasma protease in

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