SYVN1 Mouse mAbCatalog No YP-mAb-18639Isotype IgGReactivity Human,Mouse,RatApplications WBGene NameProtein NameImmunogen A synthetic peptide corresponding to a sequence within amino acids500-600ofhuman SYVN1 (NP_757385.1). SpecificityFormulationSourcePurification Affinity purificationDilution WB 1:500-2000Concentration 1 mg/mlPurity ≥90%Storage Stability -20°C/1 yearSynonyms DER3; HRD1; SYVN1Observed Band 68kDaCell PathwayTissue SpecificityFunctionBackground This gene encodes a protein involved in endoplasmic reticulum(ER)-associateddegradation. The encoded protein removes unfolded proteins, accumulatedduring ER stress, by retrograde transport to the cytosol fromtheER. Thisproteinalso uses the ubiquitin proteasome system for additional degradationof unfoldedproteins. Sequence analysis identified two transcript variants that encodedifferent isoformsmatters needingattentionAvoid repeated freezing and thawing!Usage suggestions This product can be used in immunological reaction related experiments. Formore information, please consult technical personnel.