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LG100268
  • 商城价格 登录后可查看价格
  • 货号 T19703
  • 品牌 TargetMol ( 生产厂家 )
  • CAS号 153559-76-3
  • 规格/包装 1 mg
  • 单位 瓶
  • 储存条件 -20度
  • 现货状态 现货
  • 数量

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LG100268 is a potent, selective, and orally active retinoid X receptor (RXR) agonist that agonizes RXR-α, RXR-β, and RXR-γ at the nanomolar level, selectively exceeding the RAR by three orders of magnitude.LG100268 is capable of inducing transcriptional activation in adipocytes; affecting the RXRs and their chaperone receptor, Foxl2/Dmrt1, to induce flounder masculinization in juvenile flounder; inhibits keratin 17 expression in nigrostriatal epithelial cells; and increases PD-L1 expression in HER2 or triple-negative breast cancer.
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