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产品名称 | TMEM173 Rabbit mAb |
产品货号 | AFRM9076 |
基因名称 | TMEM173 |
蛋白名称 | Transmembrane protein 173 |
其他名称 | TMEM173;ERIS;MITA;STING;Transmembrane protein 173;Endoplasmic reticulum interferon stimulator;ERIS;Mediator of IRF3 activation;hMITA;Stimulator of interferon genes protein;hSTING |
分子量 |
MW(Calculated):42kD MW(Observed):37kD |
Gene ID |
Human:340061 |
SwissPro |
Human:Q86WV6 |
宿主种属 | Rabbit |
应用范围 | WB,IHC,IF,IP,ELISA |
稀释比例 | IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200 |
反应种属 | Human,Mouse,Rat, |
克隆性 | Monoclonal |
克隆号 | AFKL9076 |
特异性 | endogenous |
同种型 | Rabbit IgG |
保存液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
纯化方式 | Protein A |
保存条件 | -20°C/1 year |
背景资料 | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014], |