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PBRM1-BD2-IN-5
  • 商城价格 登录后可查看价格
  • 货号 T60159
  • 品牌 TargetMol ( 生产厂家 )
  • CAS号 2819989-61-0
  • 规格/包装 1 mL
  • 单位
  • 储存条件 -20度
  • 现货状态 现货

  • 数量

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PBRM1-BD2-IN-5 is a potent inhibitor of the PBRM1 Bromodomain, demonstrating dissociation constant (Kd) values of 1.5 μM and 3.9 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and boasts an inhibitory concentration 50 (IC50) value of 0.26 μM for PBRM1-BD2. This compound effectively diminishes the interaction between the full-length PBRM1 and acetylated histone peptide within the PBAF complex in cell lysates, which positions it as a promising candidate for anticancer research.
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