
Applications
WB |
Human, Mouse, Rat |
1: 3000-1: 5000 |
HeLa, Jurkat, MCF-7, PC-3, HepG2 |
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
spleen, colon cancer, lung, lung cancer |
ICC/IF |
Human, Mouse, Rat |
1: 300-1: 1000 |
NIH/3T3, HeLa |
Background
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.