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The BD® OMICS-Guard Sample Preservation Buffer is a unique reagent that preserves both mRNA and protein epitopes of biological samples without the use of traditional cross-linking and harsh fixatives. The BD® OMICS-Guard Buffer is proven to preserve biological samples for both proteomic and transcriptomic studies, allowing the detection of surface and/or intracellular protein targets without compromising single-cell RNA sequencing data. The BD® OMICS-Guard Buffer can be used as a stand-alone product to preserve isolated cells, whole blood, and bulk tissues for up to 72 hours at 4°C prior to many single-cell applications (see below), or in conjunction with the BD Rhapsody™ Intracellular AbSeq Buffer Kit, which allows cells to be stored up to 24 hours at 4°C prior to permeabilization.