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Ki-67 protein, also known as MKI67, is a nuclear protein that is associated with cellular proliferation. Ki-67 protein is expressed in all cell types. It is present during active phases of the cell cycle (G1, S, G2 and mitosis) and not during the resting phase, G0. Because of this, Ki-67 is an excellent marker for determining the fraction of proliferating cells within a given population of cells.