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[KD] Cleaved-Caspase 9 Rabbit mAb

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官网http://www.zen-bio.cn/prod_view.aspx?TypeId=178&Id=655980&FId=t3:178:3

产品详情

Product Name

[KD] Cleaved-Caspase 9 Rabbit mAb
Gene ID

842
SwissProt ID

P55211
Gene Name

CASP9
Alternative Names

CASP9; MCH6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6
Background

Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit.
Research Field

Cell Biology
Product Categories

KO/KD validated
Host

Rabbit
Reactivity

Human,Mouse
Application

WB,IHC-P,ICC/IF,IP
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50
Molecular Weight

Calculated MW: 46 kDa; Observed MW: 46,39,37,35 kDa
Clonality

Monoclonal Antibody
Clonality No.

R05-4I8
Isotype

IgG
Immunogen

A synthesized peptide derived from human Caspase-9
Purification

Affinity Chromatography
Conjugation

Unconjugated
Modification

Cleaved
Form

Liquid
Buffer System

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.