Nitric oxide synthase, endothelial; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII; NOS3
Background
NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); inducible NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS).eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.
Research Field
-
Product Categories
Primary antibody
Host
Rabbit
Reactivity
Human
Application
WB, IHC-P
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/200
Molecular Weight
-
Clonality
Polyclonal Antibody
Clonality No.
-
Isotype
IgG
Immunogen
Synthetic phosphopeptide derived from human NOS3 around the phosphorylation site of Threonine 494.
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Phosphorylated
Form
Liquid
Buffer System
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
会员登录.getTime()%>){kind=logo}
购物车()
成功收藏产品
