Hemoglobin Depletion and Protein Enrichment From Dried Blood Spots Dried blood spots are useful for low volume analyses, and simple collection and transport Protocols suitable for inexpensive whole blood card systems, no need for cell separation Hemoglobin binding >90%, with 30-45 minute spin-filter format Protocols based on ≤10 µl whole blood applied, but suspension format is flexible to most volumes Blood proteins and enzymes are enriched for biomarker and proteomic investigations. Removes hemoglobin from diverse species including human, sheep, bovine, goat, rat, mouse, etc. High throughput and scaleable.