Purifies whole infectious non-enveloped virus & non-infectious enveloped virus Prepares viral samples for subsequent detection and analysis Alternative or complementary to ultracentrifugation “…love this vs sucrose cushions!” Maggie L. Bartlett, BS PhD, Johns Hopkins Bloomberg School of Public Health or can complement ultracentrifugation, for viral proteomic enrichment 350X (Fragnoud et al, 2016 http://www.ncbi.nlm.nih.gov/pubmed/26572220) Isolates antigenic virions, enveloped and non-enveloped Enriches for viral nucleic acids; detergent, chaotrope, Trizol® compatible