商品介绍

gene_symbol：CD105
Synonyms：END; HHT1; ORW1
clone_name：OTI8A1
immunogen：Full length human recombinant protein of human ENG(NP_000109) produced in HEK293T cell.
predicted_size：65 kDa
background：This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：IF, WB
Recommend Dilution：WB 1:200~4000, IF 1:100
reactivities：Human
storage：Store at -20°C as received.