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gene_symbol:PDX1
Synonyms:GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
clone_name:OTI2A12
immunogen:Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
predicted_size:30.6 kDa
background:Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, IHC, WB
Recommend Dilution:WB 1:20000, IHC 1:50, IF 1:50~100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:PDX1
Synonyms:GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
clone_name:OTI2A12
immunogen:Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
predicted_size:30.6 kDa
background:Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, IHC, WB
Recommend Dilution:WB 1:20000, IHC 1:50, IF 1:50~100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.