商品介绍

gene_symbol：L1CAM
Synonyms：CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
clone_name：OTI3G1
immunogen：Full length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.
predicted_size：140.0 kDa
background：The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：FC, IF, IHC, IP, WB
Recommend Dilution：WB 1:1000, IHC 1:50, IF 1:100, FLOW 1:100, IP 2-4ug/mg
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.