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gene_symbol:PMS2
Synonyms:HNPCC4; PMS2CL; PMSL2
clone_name:OTI2G5
immunogen:Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.
predicted_size:95.6 kDa
background:This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IF, IHC, WB
Recommend Dilution:WB 1:500, IHC 1:150, IF: 1:100
reactivities:Human
storage:Store at -20°C as received.
gene_symbol:PMS2
Synonyms:HNPCC4; PMS2CL; PMSL2
clone_name:OTI2G5
immunogen:Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.
predicted_size:95.6 kDa
background:This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IF, IHC, WB
Recommend Dilution:WB 1:500, IHC 1:150, IF: 1:100
reactivities:Human
storage:Store at -20°C as received.