商品介绍

gene_symbol：CD3E
Synonyms：IMD18; T3E; TCRE
clone_name：OTI3E10
immunogen：Full length human recombinant protein of human CD3E(NP_000724) produced in HEK293T cell.
predicted_size：20.7 kDa
background：The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：IF, IHC, WB
Recommend Dilution：WB 1:200~4000, IHC 1:150, IF 1:100
reactivities：Human
storage：Store at -20°C as received.