商品介绍

gene_symbol：Cytochrome P450 2E1
Synonyms：CPE1; CYP2E; P450-J; P450C2E
clone_name：OTI5B9
immunogen：Full length human recombinant protein of human CYP2E1 (NP_000764) produced in HEK293T cell.
predicted_size：56.8 kDa
background：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：IF, IHC, WB
Recommend Dilution：WB 1:500, IHC 1:50, IF 1:100
reactivities：Human
storage：Store at -20°C as received.