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gene_symbol:Aurora C
Synonyms:AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
clone_name:OTI10A7
immunogen:Full-length protein expressed in 293T cell transfected with human AURKC expression vector
predicted_size:35.6 kDa
background:This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:500, IF 1:100
reactivities:Human
storage:Store at -20°C as received.
gene_symbol:Aurora C
Synonyms:AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
clone_name:OTI10A7
immunogen:Full-length protein expressed in 293T cell transfected with human AURKC expression vector
predicted_size:35.6 kDa
background:This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:500, IF 1:100
reactivities:Human
storage:Store at -20°C as received.