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gene_symbol:c-Myc
Synonyms:bHLHe39; c-Myc; MRTL; MYCC
clone_name:OTI3F2
immunogen:Full length human recombinant protein of human Myc (NP_002458) produced in E.coli.
predicted_size:50.4 kDa
background:c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:IF, IHC, WB
Recommend Dilution:WB 1:1000, IHC 1:50, IF 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:c-Myc
Synonyms:bHLHe39; c-Myc; MRTL; MYCC
clone_name:OTI3F2
immunogen:Full length human recombinant protein of human Myc (NP_002458) produced in E.coli.
predicted_size:50.4 kDa
background:c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:IF, IHC, WB
Recommend Dilution:WB 1:1000, IHC 1:50, IF 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.