商品介绍

gene_symbol：MYD88
Synonyms：MYD88D
clone_name：OTI1B4
immunogen：Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.
predicted_size：33.1 kDa
background：This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2a
host：Mouse
applications：FC, IF, WB
Recommend Dilution：WB 1:2000, IF 1:100, FLOW 1:100
reactivities：Human
storage：Store at -20°C as received.