商品介绍

gene_symbol：VASP
Synonyms：vasodilator-stimulated phosphoprotein
clone_name：OTI4D6
immunogen：Full length human recombinant protein of human VASP(NP_003361) produced in 293T Cell.
predicted_size：39.6 kDa
background：Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：FC, IF, IHC, WB
Recommend Dilution：WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
reactivities：Human, Rat, Mouse
storage：Store at -20°C as received.