商品介绍

gene_symbol：SOCS3
Synonyms：ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
clone_name：OTI15F9
immunogen：Full length human recombinant protein of human SOCS3(NP_003946) produced in HEK293T cell.
predicted_size：24.6 kDa
background：This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：IHC, WB
Recommend Dilution：WB 1:2000, IHC 1:150
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.