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gene_symbol:CD163
Synonyms:M130; MM130; SCARI1
clone_name:OTI2G12
immunogen:Full length human recombinant protein of human CD163(NP_004235) produced in HEK293T cell.
predicted_size:125.3 kDa
background:The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:1000, IF 1:100
reactivities:Human
storage:Store at -20°C as received
gene_symbol:CD163
Synonyms:M130; MM130; SCARI1
clone_name:OTI2G12
immunogen:Full length human recombinant protein of human CD163(NP_004235) produced in HEK293T cell.
predicted_size:125.3 kDa
background:The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:1000, IF 1:100
reactivities:Human
storage:Store at -20°C as received