商品介绍

gene_symbol：B Raf
Synonyms：B-raf; B-RAF1; BRAF1; NS7; RAFB1
clone_name：OTI1D2
immunogen：Full length human recombinant protein of human BRAF (NP_004324) produced in HEK293T cell.
predicted_size：84.4 kDa
background：This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects,mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：FC, IF, IP, WB
Recommend Dilution：WB 1:2000, IF 1:100, Flow 1:100
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.