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gene_symbol:ERAB
Synonyms:17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD
clone_name:OTI10B4
immunogen:Full length human recombinant protein of human HSD17B10(NP_004484) produced in HEK293T cell.
predicted_size:26.9 kDa
background:This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:ERAB
Synonyms:17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD
clone_name:OTI10B4
immunogen:Full length human recombinant protein of human HSD17B10(NP_004484) produced in HEK293T cell.
predicted_size:26.9 kDa
background:This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.