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gene_symbol:SERPINB6
Synonyms:CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
clone_name:OTI1C5
immunogen:Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.
predicted_size:
background:The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IHC, WB
Recommend Dilution:WB 1:500~2000, IHC 1:150, FLOW 1:100
reactivities:Human, Monkey, Mouse
storage:Store at -20°C as received.
gene_symbol:SERPINB6
Synonyms:CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
clone_name:OTI1C5
immunogen:Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.
predicted_size:
background:The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IHC, WB
Recommend Dilution:WB 1:500~2000, IHC 1:150, FLOW 1:100
reactivities:Human, Monkey, Mouse
storage:Store at -20°C as received.