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gene_symbol:XRCC1
Synonyms:RCC
clone_name:OTI2D8
immunogen:Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
predicted_size:69.3 kDa
background:The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IHC, WB
Recommend Dilution:WB 1:2000, IHC 1:50, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:XRCC1
Synonyms:RCC
clone_name:OTI2D8
immunogen:Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
predicted_size:69.3 kDa
background:The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IHC, WB
Recommend Dilution:WB 1:2000, IHC 1:50, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.