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gene_symbol:PAICS
Synonyms:ADE2; ADE2H1; AIRC; PAIS
clone_name:OTI1B4
immunogen:Full length human recombinant protein of human PAICS (NP_006443) produced in HEK293T cell.
predicted_size:46.9 kDa
background:This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:FC, IF, WB
Recommend Dilution:WB 1:2000, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:PAICS
Synonyms:ADE2; ADE2H1; AIRC; PAIS
clone_name:OTI1B4
immunogen:Full length human recombinant protein of human PAICS (NP_006443) produced in HEK293T cell.
predicted_size:46.9 kDa
background:This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:FC, IF, WB
Recommend Dilution:WB 1:2000, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.