商品介绍

gene_symbol：COPS6
Synonyms：CSN6; MOV34-34KD
clone_name：OTI4E7
immunogen：Human recombinant protein fragment corresponding to amino acids 58-327 of human COPS6(NP_006824) produced in E.coli.
predicted_size：36 kDa
background：The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2a
host：Mouse
applications：IF, IHC, WB
Recommend Dilution：WB 1:2000, IHC 1:150, IF 1:100
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.