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gene_symbol:Melanoma gp100
Synonyms:D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
clone_name:OTI7E3
immunogen:Full length human recombinant protein of human SILV (NP_008859) produced in HEK293T cell.
predicted_size:70.3 kDa
background:Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:FC, IHC
Recommend Dilution:FLOW 1:100, IHC: 1:150
reactivities:Human
storage:Store at -20°C as received.
gene_symbol:Melanoma gp100
Synonyms:D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
clone_name:OTI7E3
immunogen:Full length human recombinant protein of human SILV (NP_008859) produced in HEK293T cell.
predicted_size:70.3 kDa
background:Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:FC, IHC
Recommend Dilution:FLOW 1:100, IHC: 1:150
reactivities:Human
storage:Store at -20°C as received.