商品介绍

gene_symbol：RASSF1
Synonyms：123F2; NORE2A; RASSF1A; RDA32; REH3P21
clone_name：OTI8E4
immunogen：Human recombinant protein fragment corresponding to amino acids 1-341 of human RASSF1(NP_009113) produced in E.coli.
predicted_size：38.6 kDa
background：This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：FC, IF, IHC, WB
Recommend Dilution：WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.