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gene_symbol:KDM4C
Synonyms:GASC1; JHDM3C; JMJD2C; TDRD14C
clone_name:OTI4B1
immunogen:Full length human recombinant protein of human KDM4C (NP_055876) produced in HEK293T cell.
predicted_size:119.8 kDa
background:This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IF, IHC
Recommend Dilution:IHC 1:50, IF 1:100, FLOW 1:100
reactivities:Human, Rat
storage:Store at -20°C as received.
gene_symbol:KDM4C
Synonyms:GASC1; JHDM3C; JMJD2C; TDRD14C
clone_name:OTI4B1
immunogen:Full length human recombinant protein of human KDM4C (NP_055876) produced in HEK293T cell.
predicted_size:119.8 kDa
background:This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IF, IHC
Recommend Dilution:IHC 1:50, IF 1:100, FLOW 1:100
reactivities:Human, Rat
storage:Store at -20°C as received.