商品介绍

gene_symbol：TRIB2
Synonyms：C5FW; GS3955; TRB2
clone_name：OTI8D11
immunogen：Full length human recombinant protein of human TRIB2 (NP_067675) produced in HEK293T cell.
predicted_size：38.8 kDa
background：This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：FC, IF, IHC, WB
Recommend Dilution：WB 1:1000~2000, IHC 1:50, IF 1:50, FLOW 1:100
reactivities：Human, Mouse
storage：Store at -20°C as received.