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gene_symbol:Dystrobrevin alpha
Synonyms:D18S892E; DRP3; DTN; DTN-A; LVNC1
clone_name:OTI1C2
immunogen:Full length human recombinant protein of human DTNA (NP_116761) produced in HEK293T cell.
predicted_size:58.7 kDa
background:The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, WB
Recommend Dilution:WB 1:2000, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:Dystrobrevin alpha
Synonyms:D18S892E; DRP3; DTN; DTN-A; LVNC1
clone_name:OTI1C2
immunogen:Full length human recombinant protein of human DTNA (NP_116761) produced in HEK293T cell.
predicted_size:58.7 kDa
background:The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, WB
Recommend Dilution:WB 1:2000, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.