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gene_symbol:KRAS
Synonyms:C-K-RAS; c-Ki-ras2; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD
clone_name:OTI2C1
immunogen:Full length human recombinant protein of human KRAS (NP_203524) produced in E.coli.
predicted_size:21.5 kDa
background:This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IHC, WB
Recommend Dilution:IHC 1:100, WB 1:2000
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:KRAS
Synonyms:C-K-RAS; c-Ki-ras2; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD
clone_name:OTI2C1
immunogen:Full length human recombinant protein of human KRAS (NP_203524) produced in E.coli.
predicted_size:21.5 kDa
background:This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IHC, WB
Recommend Dilution:IHC 1:100, WB 1:2000
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.