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gene_symbol:ATRIP
Synonyms:DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740
clone_name:OTI5E7
immunogen:Human recombinant protein fragment corresponding to amino acids 42-309 of human ATRIP(NP_569055) produced in E.coli.
predicted_size:85.7 kDa
background:The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
reactivities:Human, Dog
storage:Store at -20°C as received.
gene_symbol:ATRIP
Synonyms:DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740
clone_name:OTI5E7
immunogen:Human recombinant protein fragment corresponding to amino acids 42-309 of human ATRIP(NP_569055) produced in E.coli.
predicted_size:85.7 kDa
background:The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
reactivities:Human, Dog
storage:Store at -20°C as received.