商品介绍

gene_symbol：Livin
Synonyms：KIAP; LIVIN; ML-IAP; MLIAP; RNF50
clone_name：OTI1D12
immunogen：Full length human recombinant protein of human BIRC7 (NP_071444) produced in HEK293T cell.
predicted_size：32.8 kDa
background：The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by vepesid.
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：FC, IHC, WB
Recommend Dilution：WB 1:100, IHC 1:50, Flow 1:100
reactivities：Human
storage：Store at -20°C as received.