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gene_symbol:PON3
Synonyms:lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase
clone_name:OTI5B5
immunogen:Human recombinant protein fragment corresponding to amino acids 30-319 of human PON3(NP_000931) produced in E.coli.
predicted_size:39.4 kDa
background:This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:2000
reactivities:Human
storage:Store at -20°C as received.
gene_symbol:PON3
Synonyms:lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase
clone_name:OTI5B5
immunogen:Human recombinant protein fragment corresponding to amino acids 30-319 of human PON3(NP_000931) produced in E.coli.
predicted_size:39.4 kDa
background:This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:2000
reactivities:Human
storage:Store at -20°C as received.