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gene_symbol:Cytochrome P450 Reductase
Synonyms:CPR; CYPOR; P450R
clone_name:OTI3F10
immunogen:Full length human recombinant protein of human POR (NP_000932) produced in HEK293T cell.
predicted_size:76.9 kDa
background:This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:1000, IHC 1:50, IF 1:50~100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:Cytochrome P450 Reductase
Synonyms:CPR; CYPOR; P450R
clone_name:OTI3F10
immunogen:Full length human recombinant protein of human POR (NP_000932) produced in HEK293T cell.
predicted_size:76.9 kDa
background:This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:1000, IHC 1:50, IF 1:50~100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.