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gene_symbol:JAK3
Synonyms:JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
clone_name:OTI2B4
immunogen:Human recombinant protein fragment corresponding to amino acids 811-1124 of human JAK3 (NP_000206) produced in E.coli.
predicted_size:124.9 kDa
background:The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:500
reactivities:Human
storage:Store at -20°C as received.
gene_symbol:JAK3
Synonyms:JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
clone_name:OTI2B4
immunogen:Human recombinant protein fragment corresponding to amino acids 811-1124 of human JAK3 (NP_000206) produced in E.coli.
predicted_size:124.9 kDa
background:The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:500
reactivities:Human
storage:Store at -20°C as received.