商品介绍

gene_symbol：MLH1
Synonyms：COCA2; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1
clone_name：OTI10F9
immunogen：Human recombinant protein fragment corresponding to amino acids 1-298 of human MLH1 (NP_000240) produced in E.coli.
predicted_size：84.4 kDa
background：This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：WB
Recommend Dilution：WB 1:500
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.