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gene_symbol:Xanthine Oxidase
Synonyms:XAN1; XO; XOR
clone_name:OTI5D8
immunogen:Human recombinant protein fragment corresponding to amino acids 1-280 of human XDH (NP_000370) produced in E.coli.
predicted_size:146.2 kDa
background:Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:500
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:Xanthine Oxidase
Synonyms:XAN1; XO; XOR
clone_name:OTI5D8
immunogen:Human recombinant protein fragment corresponding to amino acids 1-280 of human XDH (NP_000370) produced in E.coli.
predicted_size:146.2 kDa
background:Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:500
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.