商品介绍

gene_symbol：Calcium Sensing Receptor
Synonyms：CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1
clone_name：
immunogen：Recombinant protein of human CASR
predicted_size：120.5 kDa
background：The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008]
buffer：PBS with 0.02% sodium azide, 50% glycerol, pH7.3
purification：Purified from the immunized serum by affinity chromatography (Protein A/G)
isotype：IgG
host：Rabbit
applications：WB
Recommend Dilution：WB: 1:500
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.