商品介绍

gene_symbol：CYB5R3
Synonyms：B5R; DIA1
clone_name：OTI1E8
immunogen：Full length human recombinant protein of human CYV5R3(NP_000389) produced in HEK293T cell.
predicted_size：34.1 kDa
background：This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：IF, IHC, WB
Recommend Dilution：WB 1:500~2000, IHC 1:150, IF 1:100
reactivities：Human
storage：Store at -20°C as received.